Found 12 matching trials
Reduced Intensity Transplantation for Severe Sickle Cell Disease PHASE2 This study is being done to test a transplant method that may have fewer si...
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St. Jude Children's Research Hospital
Treatments Being Tested
hydroxyurea, azathioprine, alemtuzumab, thioptepa, low dose total body irradiation and sirolimus hydroxyurea, azathioprine, alemtuzumab, thiotepa, plerixafor, low dose total body irradiation, cyclophosphamide and sirolimus Learn More & Join Trial
Nonmyeloablative Haploidentical Peripheral Blood Mobilized Hematopoietic Precursor Cell Transplantation for Sickle Cell Disease PHASE1 Background:
Peripheral blood stem cell transplantation procedures are used...
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Active Not Recruiting
Location
National Institutes of Health Clinical Center
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Ocrelizumab or Alemtuzumab Compared With Autologous Hematopoietic Stem Cell Transplantation in Multiple Sclerosis - a Phase-2 Randomised Controlled Trial PHASE2 A multicentre controlled phase II trial to compare the efficacy and safety ...
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Universitätsklinikum Hamburg-Eppendorf
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T Cell Depletion for Recipients of HLA Haploidentical Related Donor Stem Cell Grafts PHASE2 Subjects are being asked to participate in this study because treatment of ...
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Houston Methodist Hospital
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High Dose Chemo With Stem Cell Transplant as Treatment for Multiple Sclerosis That Failed Prior Treatment PHASE2 The purpose of this study is to evaluate the toxicity and the effectiveness...
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Amarillo Diagnostic Clinic
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Autologous Stem Cell Transplantation in Patients With Systemic Sclerosis PHASE2 The purpose of this study is to determine whether a regimen of high-dose im...
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Children's Hospital of Pittsburgh of UPMC
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Hematopoietic Stem Cell Transplantation (HSCT) for Children With SCID Utilizing Alemtuzumab, Plerixafor & Filgrastim PHASE2 The goal of this study is to develop a novel approach to hematopoietic stem...
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UCSF Benioff Children's Hospital
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Stem Cell Transplant Therapy With Campath-1H for Treating Advanced Mycosis Fungoides and Sezary Syndrome PHASE1 This study will investigate the safety and effectiveness of a modified dono...
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National Institutes of Health Clinical Center, 9000 Rockville Pike
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Base Editing for Mutation Repair in Hematopoietic Stem & Progenitor Cells for X-Linked Chronic Granulomatous Disease PHASE1 Background:
Chronic granulomatous disease (CGD) is a rare immune disorder ...
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National Institutes of Health Clinical Center
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Best Available Therapy Versus Autologous Hematopoietic Stem Cell Transplant for Multiple Sclerosis (BEAT-MS) PHASE3 This is a multi-center prospective rater-masked (blinded) randomized contro...
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Stanford Multiple Sclerosis Center
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